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Keyword(s)
Availability
Live mice
Cryopreserved embryos
Cryopreserved ovaries
Cryopreserved sperm
ES cell lines
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Domain(s)
Aging
Alcohol Abuse
Auditory/Vestibular
Circadian Rhythmicity
Drug Abuse
Emotional Behavior
Epilepsy
Eye/Vision
Growth/Development
Gustation/Olfaction
Histology
Learning/Memory
Metabolism
Movement/Neuromuscular Function
Neuroendocrine
Neuropsychiatric
Pain/Nociception
Social Behavior
Visible Mutants
Mutation Type(s)
chemically induced mutation (CI)
transgenic (TG)
targeted mutation (TM)


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MUTANT LINE NAME SYNOPSIS
GENE OR LOCUS CHROMOSOME PHENOTYPIC DOMAIN DATE AVAILABLE ORDERING INFORMATION
112TNR
Exceptional perfomance on rotarod training and performance (more)

15
Alcohol Abuse
23-Sep-2005
Contact TMGC
221CH19
Reduced ethanol preference. (more)

19
Alcohol Abuse
Gustation/Olfaction
23-Sep-2005
Contact TMGC
138TNR
Females of 138TNR consume high amounts of ethanol in part due to high consumption of liquid. (more)

15
Alcohol Abuse
Gustation/Olfaction
22-Mar-2005
Contact TMGC
158TNR
Males exhibit increased preference for ethanol and increased ethanol consumption. (more)

15
Alcohol Abuse
Gustation/Olfaction
22-Mar-2005
Contact TMGC
73TND
Consumes excess amounts of water in a two-bottle choice test. (more)

7
Alcohol Abuse
Gustation/Olfaction
29-May-2003
Contact TMGC
22TNJ
Homozygous mice display a hyperactivity phenotype: Increased locomotion and rearing in Open Field test, and enhanced hyperactivity in response to ethanol administration. High frequency hearing loss in ABR assay. (more)

15
Alcohol Abuse
Movement/Neuromuscular Function
Emotional Behavior
Auditory/Vestibular
18-Feb-2003
Contact TMGC
7TNJ
Increased locomotor activation following ethanol administration. (more)

15
Alcohol Abuse
Movement/Neuromuscular Function
14-Nov-2002
Contact TMGC
NMF370
Mutants show bi-directional circling behavior. (more)


Auditory/Vestibular
Visible Mutants
15-Jun-2006
Contact JAX-NMF
NMF430
(video available)
Deaf with head and body tilt, circling behavior. (more)
Tmhsnmf430
17
Auditory/Vestibular
Visible Mutants
Movement/Neuromuscular Function
06-Feb-2006
Contact JAX-NMF
NMF455
(video available)
Body tremor, head tossing and bi-directional circling behavior. (more)

7
Auditory/Vestibular
Movement/Neuromuscular Function
Visible Mutants
06-Feb-2006
Contact JAX-NMF
62TNW
Wide-range frequency hearing loss (more)

10
Auditory/Vestibular
22-Aug-2005
Contact TMGC
90TNI
High frequency hearing loss (more)

10
Auditory/Vestibular
22-Aug-2005
Contact TMGC
283CH19
High frequency hearing loss (more)

19
Auditory/Vestibular
22-Aug-2005
Contact TMGC
118TNE
High frequency hearing loss with wide range component. (more)

15
Auditory/Vestibular
18-Mar-2005
Contact TMGC
009TNP
Wide frequency hearing loss with circling behavior (more)

7
Auditory/Vestibular
Visible Mutants
Movement/Neuromuscular Function
22-Aug-2005
Contact TMGC
NMF371
(video available)
Circling (bi-directional), head tilt and head tossing behavior; the mutants are deaf. (more)
Myo7anmf371
7
Auditory/Vestibular
Visible Mutants
19-Sep-2005
Contact JAX-NMF
NMF333
(video available)
The mutants show head tilt and occasional head tossing behavior. (more)
nmf333
8
Auditory/Vestibular
Visible Mutants
05-Apr-2005
Contact JAX-NMF
NMF318
(video available)
The mutants are deaf, show circling and head tossing behavior. (more)
nmf318
17
Auditory/Vestibular
Visible Mutants
21-Jan-2005
Contact JAX-NMF
NMF329
The mutants are deaf. (more)
nmf329
17
Auditory/Vestibular
01-Nov-2004
Contact JAX-NMF
71TNP
Wide-range frequency hearing loss in Male mice. (more)

7
Auditory/Vestibular
18-Jan-2004
Contact TMGC
NMF219
(video available)
Circling and head tossing behavior observed by weaning age; mutants are deaf. (more)
nmf219
16
Auditory/Vestibular
Visible Mutants
28-Feb-2004
Contact JAX-NMF
NMF172
(video available)
Circling (bi-directional), head tossing behavior observed by weaning age; the mutants are deaf. (more)
nmf172
10
Auditory/Vestibular
Visible Mutants
28-Feb-2004
Contact JAX-NMF
NMF252
(video available)
Circling behavior, head tilt and tossing observed by weaning age; the mutants are deaf. (more)
Cdh23nmf252
10
Auditory/Vestibular
Visible Mutants
28-Feb-2004
Contact JAX-NMF
NMF181
(video available)
Circling, head tossing behavior; the mutants are deaf. (more)
Cdh23nmf181
10
Auditory/Vestibular
Visible Mutants
07-Nov-2003
Contact JAX-NMF
NMF190
(video available)
Circling, head tilt and head tossing behavior; the mutants are deaf. (more)
Kcne1nmf190
16
Auditory/Vestibular
Visible Mutants
04-Oct-2003
Contact JAX-NMF
NMF112
(video available)
Circling behavior, slight head tilt; mutants are deaf. (more)
Cdh23nmf112
10
Auditory/Vestibular
Visible Mutants
18-Jun-2003
Contact JAX-NMF
NMF4
Visible head tilt; slight body tremor. (more)
nmf4
15
Auditory/Vestibular
Movement/Neuromuscular Function
Visible Mutants
23-Jan-2003
Contact JAX-NMF
NMF19
(video available)
Circling behavior by weaning age, deaf by 14 weeks of age; reduced grip strength. (more)
Pcdh15nmf19
10
Auditory/Vestibular
Movement/Neuromuscular Function
Visible Mutants
21-Jan-2002
Contact JAX-NMF
Time-sheet
Wild type mice display a free running period of 23.27 hrs (+/- 0.13 sd) while mice with this mutation free run with a period of 22.4 - 22.9 hrs. (more)


Circadian Rhythmicity

Contact NU
Short-term
Wild type mice display a free running period of 23.27 hrs (+/- 0.13 sd) while heterozygous mice with this mutation free run with a period of 22.8 hrs. (more)


Circadian Rhythmicity

Contact NU
Meantime
Wild type mice display a free running period of 23.27 hrs (+/- 0.13 sd) while mice with this mutation free run with a period of 22.2-22.7 hrs. (more)


Circadian Rhythmicity

Contact NU
dinner-time
Animals do not have a distinct onset of activity; activity pattern is dissociated. (more)


Circadian Rhythmicity

Contact NU
swingshift
Animals have innapropriate bouts of activity during the light portion of the circadian assay. (more)


Circadian Rhythmicity

Contact NU
Short-time
Shortened period (more)


Circadian Rhythmicity

Contact NU
mper1::Luc
Hemizygous mouse exhibits CD-1 wild-type phenotype. This mouse can be utilized as a reporter line for mper1 transcription. (more)


Circadian Rhythmicity
01-May-2005
Contact NU
Time-course
Short circadian free-running period in constant darkness. (more)


Circadian Rhythmicity

Contact NU
Time-trial
Short circadian free-running period in constant darkness. (more)


Circadian Rhythmicity

Contact NU
Timetraveler
Long circadian free-running period in constant darkness. (more)


Circadian Rhythmicity

Contact NU
Past-time
Short circadian free-running period in constant darkness. (more)


Circadian Rhythmicity

Contact NU
Timemachine
Short circadian free-running period in constant darkness. (more)


Circadian Rhythmicity

Contact NU
Time-share
Short circadian free-running period in constant darkness. (more)


Circadian Rhythmicity

Contact NU
Half-time
Short circadian free-running period in constant darkness. (more)


Circadian Rhythmicity

Contact NU
Clock-transgenic
Over-expression of the wild-type Clock message rescues long period and loss-of-rhythm phenotypes in Clock mutant mice. (more)


Circadian Rhythmicity
01-May-2005
Contact NU
mper2::Luc
Homozygotes exhibit the wildtype phenotype. Used as a model to monitor PER protein in vitro and in vivo. (more)


Circadian Rhythmicity
01-May-2005
Contact NU
part-time
Shortened free-running period with 1.6 hr shorter in heterozygous mice. (more)

10
Circadian Rhythmicity
01-Aug-2002
Contact NU
Overtime
Lengthened free-running period with 2.8 hr longer in homozygous and 0.9 hr longer in heterozygous mice. (more)


Circadian Rhythmicity
01-Aug-2002
Contact NU
Clock
Lengthens circadian period by 1 hour in heterozygotes and by 4 hours in homozygotes. Homozygotes lose persistent circadian rhythm in constant darkness. (more)

5
Circadian Rhythmicity
01-May-2005
Contact NU
116TNE
Reduced locomotor stimulation in response to cocaine. (more)

15
Drug Abuse
Movement/Neuromuscular Function
01-Mar-2005
Contact TMGC
4TNJ
Reduced locomotor stimulation in response to cocaine. (more)

15
Drug Abuse
Movement/Neuromuscular Function
16-Jan-2004
Contact TMGC
223CH19
Decreased anxiety related behavior in light/dark task. (more)

19
Emotional Behavior
23-Sep-2005
Contact TMGC
252TNR
Increased tail-suspension immobility. (more)

15
Emotional Behavior
23-Sep-2005
Contact TMGC
40TNP
Increased tail suspension immobility. (more)

7
Emotional Behavior
03-Jun-2003
Contact TMGC
276TNP
Homozygous mice are mutant for Behavioral Despair/Anxiety as demonstrated by increased tail suspension immobility, and Social Behavior: females show enhanced preference for same-sex conspecific odors. (more)

7
Emotional Behavior
Social Behavior
14-Nov-2002
Contact TMGC
22TNP
Increased tail-suspension immobility and tendency toward increased activity in the open field. (more)

7
Emotional Behavior
Movement/Neuromuscular Function
14-Nov-2002
Contact TMGC
NMF134
Low threshold to electroconvulsive minimal clonic seizures. (more)
Nmf134
2
Epilepsy
29-May-2003
Contact JAX-NMF
NMF88
Low threshold to electroconvulsive minimal clonic seizures. (more)
nmf88
2
Epilepsy
29-May-2003
Contact JAX-NMF
SZT1
Heterozygotes have low threshold for electroconvulsive and PTZ-induced seizures; homozygotes show perinatal lethality. (more)
Szt1
2
Epilepsy
05-Mar-2003
Contact JAX-NMF
NMF31
Heterozygotes have high threshold to electroconvulsive minimal clonic seizures. (more)
Nmf31
1
Epilepsy
09-Feb-2003
Contact JAX-NMF
NMF268
White retinal spots. (more)


Eye/Vision
07-Feb-2006
Contact JAX-NMF
NMF246
Grainy retina, retinal spots. (more)


Eye/Vision
02-Feb-2006
Contact JAX-NMF
NMF282
Retinal spots. (more)


Eye/Vision
02-Feb-2006
Contact JAX-NMF
serg4
All waves of ERG are undetectable or very small at 12 weeks of age. (more)


Eye/Vision

Contact NU
serg3
All waves of ERG are undetectable or very small at 12 weeks of age. (more)


Eye/Vision

Contact NU
serg2
All waves of ERG are undetectable or very small at 12 weeks of age. (more)


Eye/Vision

Contact NU
serg1
All waves of ERG are undetectable or very small at 12 weeks of age. (more)


Eye/Vision

Contact NU
nob4
Mutant mice have an ERG at 12 weeks that lacks rod b-wave and scotopic threshold response(STR), cone ERG has large amplitude. (more)


Eye/Vision
18-Oct-2005
Contact NU
biga1
a-wave of electroretinogram (ERG) is almost twice the normal peak amplitude at 12 weeks of age. Other waves are normal. (more)


Eye/Vision

Contact NU
NMF195
Grainy retina. (more)


Eye/Vision
21-Apr-2005
Contact JAX-NMF
NMF247
Retinal spots, vitreal fibroplasia. (more)
nmf247
14
Eye/Vision
27-Dec-2004
Contact JAX-NMF
NMF191
Grainy retina. (more)
Nmf191
4
Eye/Vision
27-Dec-2004
Contact JAX-NMF
NMF240
Mottled retina and atrophied retinal blood vessels. (more)


Eye/Vision
17-Nov-2004
Contact JAX-NMF
NMF131
Hyaloid remnants and vitreal fibroplasia with white retinal spots. (more)


Eye/Vision
14-Sep-2004
Contact JAX-NMF
203CH19
Simple congenital micropthalmia (low eye weight). (more)

19
Eye/Vision
16-Jan-2004
Contact TMGC
NMF166
Lens extrusion cataract and deep anterior chamber. (more)
nmf166
4
Eye/Vision
24-Apr-2004
Contact JAX-NMF
NMF193
Mottled retina indicative of pan retinal photoreceptor degeneration. (more)


Eye/Vision
24-Apr-2004
Contact JAX-NMF
NMF192
Retinal spots, mottled retinae. (more)


Eye/Vision
28-Feb-2004
Contact JAX-NMF
NMF128
The mutants show spots on retina and in vitreous body. (more)


Eye/Vision
26-Dec-2003
Contact JAX-NMF
NMF144
Retinal spots; the phenotype represents a Crb1rd8like mutation, however the expression is milder in NMF144 than that observed in Crb1rd8mutants. (more)
Crb1rd8
1
Eye/Vision
13-Dec-2003
Contact JAX-NMF
117TNP
Hypopigmentation of the fundus with disruption of the RPE and choroid. (more)

7
Eye/Vision
Histology
29-May-2003
Contact TMGC
47TNT
Pale optic disk with hypervascularization of optic nerve. (more)

15
Eye/Vision
Histology
29-May-2003
Contact TMGC
28TNP
Hyperpigmentation around optic disk with abnormal retinal vascularization. (more)

7
Eye/Vision
Histology
29-May-2003
Contact TMGC
163TNP
Hypopigmentation of the fundus with disruption of the RPE and choroid. (more)

7
Eye/Vision
Histology
19-May-2003
Contact TMGC
135TNP
Hypopigmentation of the fundus with disruption of the RPE and choroid. (more)

7
Eye/Vision
Histology
31-May-2003
Contact TMGC
NMF137
Mottled retina, white retinal vessels. (more)
Pde6bnmf137
5
Eye/Vision
27-Jun-2003
Contact JAX-NMF